Some Research has advised that SAMe could be as handy because the prescription antidepressants imipramine and escitalopram, but much more investigation is important. Aerobic exercise raises endorphin amounts and stimulates neurotransmitters, probably easing depression and anxiety. A 2019 paper states that exercise can be In particular handy with treatment-resistant depression. https://radianthealthvibes.com/somatic-therapy-exercises/